PANA RealTyper™ CRE

Carbapenem-resistant Enterobacteriaceae (CRE) is Gram-negative bacterium that is resistant to the carbapenem class of antibiotics, considered the drugs of last resort for such infections. Rapid and accurate CRE detection/identification testing is important for proper antibiotic prescription and rapid treatment.PANA RealTyper™ CRE Kit can accurately detect and genotype 6 types of CRE in a short time (within 3 hours).

CAT NO.

PNAM-4001

DETAILS

PROCEDURE

• sample preparation
• Extraction of Total
• Amplification of target DNA by Real-Time PCR
• Analysis of Result

COMPATIBLE SAMPE TYPE

COMPATIBLE Real-Time PCR machine

• 

  CFX96
  (Bio-Rad)

• 

  QuantStudio5
  (Thermo Fisher Scientific)

REFERENCE

• Nordmann, P et al.(2011)Emerg Infect Dis, 17(10):1791-1798
  
  Global Spread of Carbapenemase-producing Enterobacteriaceae.

  PubMed Article
• Mendes, R. E et al.(2006)J Clin Microbiol, 45 (2):544-547
  
  Rapid detection and identification of metallo-β-lactamase-encoding genes by multiplex real-time PCR assay and melt curve analysis.

  PubMed Article
• Ulyashova, M. M et al.(2010)Acta Naturae, 2 (3):101-109
  
  Oligonucleotide microarray for the identification of carbapenemase genes of molecular classes A, B, and D.

  PubMed
• Hirakata, Y et al.(1998)Antimicrob Agents Chemother, 42 (8):2006-2011
  
  Rapid detection and evaluation of clinical characteristics of emerging multipledrug-resistant Gram-negative rods Carrying the Metallo-β-Lactamase Genebla IMP.

  PubMed Article
• Yang, Q et al.(2016)PLoS One, 11(7):e0158958
  
  Two Multiplex Real-Time PCR Assays to Detect and Differentiate Acinetobacter baumannii and Non-baumannii Acinetobacter spp. Carrying blaNDM, blaOXA-23-Like, blaOXA-40-Like, blaOXA-51-Like, and blaOXA-58-Like Genes.

  PubMed Article

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