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Oncology - Tissue biopsy

PANAMutyper™ Screening Kit EML4-ALK

PANAMutyper™ EML4-ALK Screening Kit is the qualitative diagnostic test kit which is able to detect 16 different EML4-ALK fusion genes of tissue from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system. The PANAMutyper™ EML4-ALK Screening Kit is intended as an aid for screening EML4-ALK fusion-positive NSCLC patients who would be sensitive for receiving ALK inhibitor therapy such as crizotinib.
CAT NO.
PNAR-5001

DETAILS

 

 


 

The PANAMutyper™ EML4-ALK Screening Kit is an in vitro diagnostic reagent for detecting 16 different EML4-ALK fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients. 

 

 No.

 EML4-ALK Fusion Types

1

E2;A20 

2

 E2;ins117A20

3

 E6;A20

 4 

 E6ins33;A20

5

 E6;ins18A20

6

 E6;A19

7

 E13;ins69A20

8

 E13;A20

9

 E14ins11;del49A20

10

 E14;del14A20

11

 E14ins2;ins56A20

12

 E17;ins30A20

13

 E17ins61;ins34A20

14

 E18;A20

15

 E20;A20

16

E20;ins18A20 

 

FEATURES

  • 01One-step RT-PCR technology
  • 02Detection of 16 EML4-ALK fusion gene variants in one tube reaction
  • 03High sensitivity, specificity and reproducibility
  • 04Short running time
  • 05Simple workflow
  • 06Easy result reading by automatic analyzing program

PROCEDURE

  • Total RNA extraction
  • Sample preperation
  • RT-PCR(real-time)
  • Analysis of result

COMPATIBLE SAMPE TYPE

- Formalin-fixed paraffin-embedded(FFPE) tissue
- Fresh tissue and biopsy sample

COMPATIBLE Real-Time PCR machine

  • CFX96
(Bio-Rad)의 이미지

    CFX96
    (Bio-Rad)

  • QuantStudio5
(ThermoFisher Scientific)의 이미지

    QuantStudio5
    (ThermoFisher Scientific)

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