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Oncology - Tissue biopsy
PNAClamp™ Mutation Detection Kit TERT
The presence of TERT mutation is a prognostic and predictive biomarker in patients with cancer such as the central nervous system, bladder, thyroid, skin, etc., associated with tumor recurrence and survival.
With its features of detection limit as low as 5% copies/rxn, the PNAClamp™ TERT Mutation Detection Kit is the qualitative diagnostic test kit which is able to detect 2 different types of TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues using peptide nucleic acid (PNA)-mediated real-time PCR clamping technology.
With its features of detection limit as low as 5% copies/rxn, the PNAClamp™ TERT Mutation Detection Kit is the qualitative diagnostic test kit which is able to detect 2 different types of TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues using peptide nucleic acid (PNA)-mediated real-time PCR clamping technology.
CAT NO.
PNAC-9001
DETAILS
The PNAClamp™ TERT Mutation Detection Kit is an in vitro diagnostic reagent for detecting 2 different TERT promoter mutations of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from patients with cancer such as the central nervous system, bladder, thyroid, skin, etc.
Mutation |
Nucleotide change |
C228 |
c.1-124C>T |
C250 |
c.1-146C>T |
FEATURES
- 01Detection of 2 TERT promoter mutations
- 02High sensitivity, specificity and reproducibility
- 03Short running time
- 04Simple workflow
- 05Easy result reading by automatic analyzing program
PROCEDURE
Sample preparation
Extraction of total DNA
Amplification of target DNA by Real-Time PCR
Analysis of Result
COMPATIBLE SAMPE TYPE
- Formalin-fixed paraffin-embedded(FFPE) tissue
- Fresh tissue and biopsy sample
- Fresh tissue and biopsy sample
COMPATIBLE Real-Time PCR machine
CFX96
(Bio-Rad)
