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Oncology - Tissue biopsy

PANAMutyper™ Screening Kit ROS1

PANAMutyper™ ROS1 Screening Kit is the qualitative diagnostic test kit which is able to detect 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue, fresh tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system.

The PANAMutyper™ ROS1 Screening Kit is intended as an aid for screening ROS1 fusion-positive NSCLC patients who would be sensitive for receiving ROS1 inhibitor therapy such as crizotinib, Lorlatinib, etc.
CAT NO.
PNAR-6001

DETAILS

 

 


The PANAMutyper™ ROS1 Screening Kit is an invitro diagnostic device for detecting 20 different ROS1 fusion genes of formalin-fixed paraffin-embedded (FFPE) tissue fresh, tissues and biopsy tissues from non-small cell lung cancer (NSCLC) patients. 

 

 no.

ROS1 Fusion Types 

Partner last observed exon

ROS1 first observed exon 

 1

CD6-R32

 CD74 exon 6

exon 32

 2

CD6-R34

exon 34

 3

EZ10-R34

EZR exon 10 

exon 34

 4

SL4-R32

 SLC34A2 exon 4

exon 32

 5

SL4-R34

exon 34

 6

SL13del-R32

 SLC34A2 exon 13del

exon 32

 7

SL13del-R34 

exon 34

 8

SD2-R34

 SDC4 exon 2

exon 32

 9

SD2-R34

exon 34

 10

SD4-R32

 SDC4 exon 4

exon 32

 11

SD4-R34

exon 34

 12

TP2-R35 

 TPM3 exon 2

exon 35

 13

TP2-R36

exon 36

 14

TP8-R35

 TPM3 exon 8

exon 35

 15

TP8-R36

exon 36

 16

GO4-R35

 GOPC exon 4

exon 35 

 17

GO4-R36

exon 36

 18

GO8-R35

GOPC exon 8 

exon 35 

 19

GO8-R36

exon 36

 20

LR16-R35

 LRIG3 exon 16

exon 35

 

 

 

FEATURES

  • 01One-step RT-PCR technology
  • 02Detection of 20 ROS1 fusion gene variants in two tube reaction
  • 03High sensitivity, specificity and reproducibility
  • 04Short running time
  • 05Simple workflow
  • 06Easy result reading by automatic analyzing program

PROCEDURE

  • Extraction of total RNA
  • PCR preparation
  • Real-time PCR(RT)
  • Analysis of result

COMPATIBLE SAMPE TYPE

Formalin-fixed paraffin-embedded(FFPE) tissue
Fresh tissue and biopsy

COMPATIBLE Real-Time PCR machine

  • CFX96
(Bio-Rad)의 이미지

    CFX96
    (Bio-Rad)

  • QuantStudio5
(Thermo Fisher Scientific)의 이미지

    QuantStudio5
    (Thermo Fisher Scientific)

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